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KMID : 0360220150560060931
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Journal of the Korean Ophthalmological Society
2015 Volume.56 No. 6 p.931 ~ p.937
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Combined Phacoemulsification, Synechiolysis without Gonioprism Lens and Intracameral Tissue Plasminogen Activator Injection for Angle-Closure Glaucoma
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Cho Seok-Ho
Kee Chang-Won
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Abstract
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Purpose: In this study we evaluated the safety and efficacy of combined phacoemulsification and synechiolysis without aid of gonioprism lens and intraoperative intracameral tissue plasminogen activator (tPA) injection for angle-closure glaucoma.
Methods: The method used in this study was synechiolysis with Kuglen hook without aid of gonioprism lens and intraoperative intracameral tPA injection following cataract surgery.
Results: A total of 20 patients with a mean age of 71.4 ± 5.4 years were treated. Mean follow-up time was 31.3 ± 24.3 months. Mean preoperative and last visit intraocular pressures (IOPs) were 21.70 ± 9.50 mm Hg and 12.40 ± 2.30 mm Hg, respectively (p < 0.0001). The mean number of glaucoma medications decreased from 2.40 to 0.30 (p < 0.0001). IOP was maintained below 16 mm Hg in all cases. No significant intraoperative and postoperative complications, hyphema, or fibrin reaction occurred.
Conclusions: Combined phacoemulsification and peripheral anterior synechiolysis with Kuglen hook without aid of gonioprism lens and intraoperative intracameral tPA injection is an effective and safe surgical procedure.
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KEYWORD
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Angle-closure glaucoma, Fibrin reaction, Synechiolysis, Tissue plasminogen activator
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